منابع مشابه
Stereoconvergent Arylations and Alkenylations of Unactivated Alkyl Electrophiles: Catalytic Enantioselective Synthesis of Secondary Sulfonamides and Sulfones
The development of efficient methods for the generation of enantioenriched sulfonamides and sulfones is an important objective for fields such as organic synthesis and medicinal chemistry; however, there have been relatively few reports of direct catalytic asymmetric approaches to controlling the stereochemistry of the sulfur-bearing carbon of such targets. In this report, we describe nickel-ca...
متن کاملStructure-activity of sulfones and sulfonamides on dihydropteroate synthetase from Neisseria meingitidis.
The molecular interaction of various sulfones and sulfonamides with partially purified dihydropteroate synthetase from Neisseria meningitidis M-166 has been examined. The mode of action of the sulfones was similar to that of the sulfonamides. Both groups of drugs were competitive inhibitors of dihydropteroate synthetase with respect to p-aminobenzoate in a partially purified enzyme preparation....
متن کاملInhibition of dihydropteroate synthetase from Escherichia coli by sulfones and sulfonamides.
The inhibitory action of various diphenylsulfones and sulfonamides on dihydropteroate synthetase partially purified from Escherichia coli was examined. 4,4'-Diaminodiphenylsulfone (DDS; I(50) = 2 x 10(-5) M) and the monosubstituted derivatives 4-amino-4'-formamidodiphenylsulfone (I(50) = 5.8 x 10(-5) M) and 4-amino-4'-acetamidodiphenylsulfone (I(50) = 5.2 x 10(-5) M) were effective inhibitors o...
متن کاملReductive cleavage of sulfones and sulfonamides by a neutral organic super-electron-donor (S.E.D.) reagent.
The sulfonyl group finds extensive applications in organic and medicinal chemistry both in sulfonamides, popular as robust protecting groups for amines,1 and in sulfones.2 Frequently, sulfones are introduced into synthetic schemes to assist particular transformations; further progress along the synthetic route can later require the removal of a sulfone group, and this can be achieved by reducti...
متن کاملSyntheses and Characterization of Cadmium (II) Oxide Nanostructure from two Nano-sized Cadmium (II) Coordination Polymers
Two nano-sized mixed-ligand Cd (II) coordination polymers; [Cd (4,4' -bpy) (C4H4O4)].1/4 H2O (1) and[Cd(bpy)1.5 (NO3)2].3H2O (2) (bpy=bipiridine) were synthesized by a sonochemical method and characterized by elemental analyses, thermal gravimetric analysis (TGA), differential thermal analysis (DTA), scanning electron microscopy (SEM) and Fourier transform infrared spectroscopy (FT-IR). The cry...
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ژورنال
عنوان ژورنال: YAKUGAKU ZASSHI
سال: 1949
ISSN: 0031-6903,1347-5231
DOI: 10.1248/yakushi1947.69.1_27